PT  - JOURNAL ARTICLE
AU  - Javier Mora-Macías
AU  - Jonathan Odilón Ojeda-Rivera
AU  - Dolores Gutiérrez-Alanís
AU  - Lenin Yong-Villalobos
AU  - Araceli Oropeza-Aburto
AU  - Javier Raya González
AU  - Gabriel Jiménez-Domínguez
AU  - Gabriela Chávez-Calvillo
AU  - Rubén Rellán-Álvarez
AU  - Luis Herrera-Estrella
TI  - Malate-dependent Fe accumulation is a critical checkpoint in the root developmental response to low phosphate
AID  - 10.1101/095497
DP  - 2016 Jan 01
TA  - bioRxiv
PG  - 095497
4099  - http://biorxiv.org/content/early/2016/12/19/095497.short
4100  - http://biorxiv.org/content/early/2016/12/19/095497.full
AB  - Low phosphate (Pi) availability constrains plant development and crop production in both natural and agricultural ecosystems. When Pi is scarce, modifications of root system architecture (RSA) enhance soil exploration ability and can lead to an increase in Pi uptake. In Arabidopsis, an iron-dependent determinate developmental program that induces premature differentiation in the root apical meristem (RAM) begins when the root tip contacts low Pi media, resulting in a short-root phenotype. However, the mechanisms that enable the regulation of root growth in response to Pi-limiting conditions remain largely unknown. Cellular, genomic and transcriptomic analysis of low-Pi insensitive mutants revealed that the malate-exudation related genes SENSITIVE TO PROTON RHIZOTOXICITY (STOP1) and ALUMINUM ACTIVATED MALATE TRANSPORTER 1 (ALMT1) represent a critical checkpoint in the root developmental response to Pi starvation in Arabidopsis thaliana.