PT - JOURNAL ARTICLE AU - Hannah M. Moots AU - Margaret Antonio AU - Susanna Sawyer AU - Jeffrey P. Spence AU - Victoria Oberreiter AU - Clemens L. Weiß AU - Michaela Lucci AU - Yahia Mehdi Seddik Cherifi AU - Francesco La Pastina AU - Francesco Genchi AU - Elisa Praxmeier AU - Brina Zagorc AU - Olivia Cheronot AU - Kadir T. Özdoğan AU - Lea Demetz AU - Selma Amrani AU - Francesca Candilio AU - Daniela De Angelis AU - Gabriella Gasperetti AU - Daniel Fernandes AU - Ziyue Gao AU - Mounir Fantar AU - Alfredo Coppa AU - Jonathan K. Pritchard AU - Ron Pinhasi TI - A Genetic History of Continuity and Mobility in the Iron Age Central Mediterranean AID - 10.1101/2022.03.13.483276 DP - 2022 Jan 01 TA - bioRxiv PG - 2022.03.13.483276 4099 - http://biorxiv.org/content/early/2022/08/23/2022.03.13.483276.short 4100 - http://biorxiv.org/content/early/2022/08/23/2022.03.13.483276.full AB - The Iron Age saw the expansion of Phoenician and Greek colonies across the Mediterranean and the rise of Carthage as the major maritime power of the region. These events were facilitated by the ease of long-distance travel following major advances in seafaring. We know from the archaeological record that trade goods and materials were moving across great distances in unprecedented quantities, but it is unclear how these patterns correlate with human mobility. To investigate population mobility and interactions directly, we sequenced the genomes of 30 ancient individuals from Carthaginian and Etruscan port cities around the central Mediterranean, in Tunisia, Sardinia, and central Italy. At all three locations, there is a meaningful contribution of autochthonous populations (from Bronze Age North Africa, Sardinia, and Italy, respectively), as well as highly heterogeneous ancestry including many individuals with ancestry from other parts of the Mediterranean region. These results highlight both the role of autochthonous populations and the extreme interconnectedness of populations in the Iron Age Mediterranean. By studying these trans-Mediterranean neighbors together, we explore the complex interplay between local continuity and mobility that shaped the Iron Age societies of the central Mediterranean.Competing Interest StatementThe authors have declared no competing interest.