TY - JOUR T1 - MHC class I and MHC class II reporter mice enable analysis of immune oligodendroglia in mouse models of multiple sclerosis JF - bioRxiv DO - 10.1101/2022.09.27.509669 SP - 2022.09.27.509669 AU - Em P Harrington AU - Riley B Catenacci AU - Matthew D Smith AU - Dongeun Heo AU - Cecilia E Miller AU - Keya R Meyers AU - Jenna Glatzer AU - Dwight E Bergles AU - Peter A Calabresi Y1 - 2022/01/01 UR - http://biorxiv.org/content/early/2022/09/28/2022.09.27.509669.abstract N2 - Oligodendrocytes and their progenitors upregulate MHC pathways in response to inflammation, but the frequency of this phenotypic change is unknown and the features of these immune oligodendroglia are poorly defined. We generated MHC class I and II transgenic reporter mice to define their dynamics in response to inflammatory demyelination, providing a means to monitor MHC activation in diverse cell types in living mice and define their roles in aging, injury and disease.Competing Interest StatementThe authors have declared no competing interest. ER -