PT  - JOURNAL ARTICLE
AU  - Liberty S. Hamilton
AU  - Erik Edwards
AU  - Edward F. Chang
TI  - Parallel streams define the temporal dynamics of speech processing across human auditory cortex
AID  - 10.1101/097485
DP  - 2017 Jan 01
TA  - bioRxiv
PG  - 097485
4099  - http://biorxiv.org/content/early/2017/01/03/097485.short
4100  - http://biorxiv.org/content/early/2017/01/03/097485.full
AB  - To derive meaning from speech, we must extract multiple dimensions of concurrent information from incoming speech signals, including phonetic and prosodic cues. Equally important is the detection of acoustic cues that give structure and context to the information we hear, such as sentence boundaries. How the brain organizes this information processing is unknown. Here, using data-driven computational methods on an extensive set of high-density intracranial recordings, we reveal a large-scale partitioning of the entire human speech cortex into two spatially distinct regions that detect important cues for parsing natural speech. These caudal (Zone 1) and rostral (Zone 2) regions work in parallel to detect onsets and prosodic information, respectively, within naturally spoken sentences. In contrast, local processing within each region supports phonetic feature encoding. These findings demonstrate a fundamental organizational property of the human auditory cortex that has been previously unrecognized.