PT  - JOURNAL ARTICLE
AU  - Janani Durairaj
AU  - Joana Pereira
AU  - Mehmet Akdel
AU  - Torsten Schwede
TI  - What is hidden in the darkness? Characterization of AlphaFold structural space
AID  - 10.1101/2022.10.11.511548
DP  - 2022 Jan 01
TA  - bioRxiv
PG  - 2022.10.11.511548
4099  - http://biorxiv.org/content/early/2022/10/13/2022.10.11.511548.short
4100  - http://biorxiv.org/content/early/2022/10/13/2022.10.11.511548.full
AB  - The recent public release of the latest version of the AlphaFold database has given us access to over 200 million predicted protein structures. We use a “shape-mer” approach, a structural fragmentation method analogous to sequence k-mers, to describe these structures and look for novelties - both in terms of proteins with rare or novel structural composition and possible functional annotation of under-studied proteins. Data and code will be made available at https://github.com/TurtleTools/afdb-shapemer-darknessCompeting Interest StatementThe authors have declared no competing interest.