PT - JOURNAL ARTICLE AU - Kim, Dongjae AU - Schütt, Heiko H. AU - Ma, Wei Ji TI - Reward prediction error neurons implement an efficient code for reward AID - 10.1101/2022.11.03.515104 DP - 2022 Jan 01 TA - bioRxiv PG - 2022.11.03.515104 4099 - http://biorxiv.org/content/early/2022/11/04/2022.11.03.515104.short 4100 - http://biorxiv.org/content/early/2022/11/04/2022.11.03.515104.full AB - We apply efficient coding principles to derive the optimal population of neurons to encode rewards from a distribution. Similar to this optimal population, dopaminergic reward prediction error neurons have a broad distribution of optimistically placed thresholds, neurons with higher thresholds have higher gain and the curvature of their responses depends on the threshold. Thus, these neurons may broadcast an efficient reward signal, not necessarily a reward prediction error.Competing Interest StatementThe authors have declared no competing interest.