TY - JOUR T1 - A primary sensory cortical interareal feedforward inhibitory circuit for tacto-visual integration JF - bioRxiv DO - 10.1101/2022.11.04.515161 SP - 2022.11.04.515161 AU - Simon Weiler AU - Vahid Rahmati AU - Marcel Isstas AU - Johann Wutke AU - Andreas Walter Stark AU - Christian Franke AU - Christian Geis AU - Otto W. Witte AU - Mark Hübener AU - Jürgen Bolz AU - Troy W. Margrie AU - Knut Holthoff AU - Manuel Teichert Y1 - 2022/01/01 UR - http://biorxiv.org/content/early/2022/11/04/2022.11.04.515161.abstract N2 - Tactile sensation and vision are often both utilized for the exploration of objects that are within reach though it is not known whether or how these two distinct sensory systems might combine such information. Here in mice we find that stimulation of the contralateral whisker array suppresses visually evoked activity in a subarea of primary visual cortex (VISp) whose visual space covers the whisker search space. This is mediated by local fast spiking interneurons that receive a direct cortico-cortical input predominantly from layer 6 of the primary somatosensory barrel cortex (SSp-bfd). These data demonstrate functional convergence within and between two primary sensory cortical areas for multisensory object detection and recognition.Competing Interest StatementThe authors have declared no competing interest. ER -