%0 Journal Article %A Houxiang Zhu %A Emily Richmond %A Chun Liang %T CRISPR-RT: A web service for designing CRISPR-C2c2 crRNA with improved target specificity %D 2017 %R 10.1101/099895 %J bioRxiv %P 099895 %X CRISPR-Cas systems have been successfully applied in genome editing. Recently, the CRISPR-C2c2 system has been reported as a tool for RNA editing. Here we describe CRISPR-RT (CRISPR RNA-Targeting), the first web service to help biologists design the crRNA with improved target specificity for the CRISPR-C2c2 system. CRISPR-RT allows users to set up a wide range of parameters, making it highly flexible for current and future research in CRISPR-based RNA editing. CRISPR-RT covers major model organisms and can be easily extended to cover other species. CRISPR-RT will empower researchers in RNA editing. It is available at http://bioinfolab.miamioh.edu/CRISPR-RT. %U https://www.biorxiv.org/content/biorxiv/early/2017/01/12/099895.full.pdf