PT  - JOURNAL ARTICLE
AU  - Morris Vanegas
AU  - Miguel Mireles
AU  - Edward Xu
AU  - Shijie Yan
AU  - Qianqian Fang
TI  - A compact breast shape acquisition system for improving diffuse optical tomography image reconstructions
AID  - 10.1101/2022.11.20.517255
DP  - 2022 Jan 01
TA  - bioRxiv
PG  - 2022.11.20.517255
4099  - http://biorxiv.org/content/early/2022/11/20/2022.11.20.517255.short
4100  - http://biorxiv.org/content/early/2022/11/20/2022.11.20.517255.full
AB  - Diffuse optical tomography (DOT) has been investigated for diagnosing malignant breast lesions but its accuracy relies on model-based image reconstructions which in turn depends on the accuracy of breast shape acquisition. In this work, we have developed a dual-camera structured light imaging (SLI) breast shape acquisition system tailored for a mammography-like compression setting. Illumination pattern intensity is dynamically adjusted to account for skin tone differences while thickness-informed pattern masking reduces artifacts due to specular reflections. This compact system is affixed to a rigid mount that can be installed into existing mammography or parallel-plate DOT systems without the need for camera-projector re-calibration. Our SLI system produces sub-millimeter resolution with a mean surface error of 0.26 mm. This breast shape acquisition system results in more accurate surface recovery, with an average 1.6-fold reduction in surface estimation errors over a reference method via contour extrusion. Such improvement translates to 25% to 50% reduction in mean squared error in the recovered absorption coefficient for a series of simulated tumors 1-2 cm below the skin.Competing Interest StatementThe authors have declared no competing interest.