RT Journal Article
SR Electronic
T1 DrosOmics: a comparative genomics browser to explore omics data in natural populations of <em>D. melanogaster</em>
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2022.07.22.501088
DO 10.1101/2022.07.22.501088
A1 Marta Coronado-Zamora
A1 Judit Salces-Ortiz
A1 Josefa González
YR 2022
UL http://biorxiv.org/content/early/2022/11/24/2022.07.22.501088.abstract
AB The advent of long-read sequencing technologies has allowed the generation of multiple high-quality de novo genome assemblies for multiple species, including well-known model species such as Drosophila melanogaster. Genome assemblies for multiple individuals of the same species are key to discover the genetic diversity present in natural populations, especially the one generated by transposable elements, the most common type of structural variant. Despite the availability of multiple genomic datasets for D. melanogaster populations, we lack an efficient visual tool to display different genomes assemblies simultaneously. In this work, we present DrosOmics, a comparative genomics-oriented browser for 52 high-quality reference genomes of D. melanogaster, including annotations from a highly reliable set of transposable elements, and functional transcriptomics and epigenomics data for half the populations. DrosOmics is based on JBrowse 2, which allows the visualization of multiple assemblies at once, key to unraveling structural and functional features of D. melanogaster natural populations.Competing Interest StatementThe authors have declared no competing interest.