RT Journal Article
SR Electronic
T1 Supply-driven evolution explains the locking-in of structures that open new evolutionary possibilities, such as higher hierarchies of organization
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2022.07.18.500397
DO 10.1101/2022.07.18.500397
A1 Julian Z. Xue
A1 Leonid Chindelevich
A1 Frédéric Guichard
YR 2022
UL http://biorxiv.org/content/early/2022/11/29/2022.07.18.500397.abstract
AB Many well-documented macro-evolutionary phenomena, such as increases in organization hierarchy, or sudden and episodic creation of new taxa, still challenge current evolutionary theories. Here we show a new mechanism that can explain them. We begin by showing how the order of mutations can alter evolutionary trajectories. We present a framework integrating both mutation and environmental biases and show that mutation bias can strongly outweigh any environmental bias, a regime we call “supply-driven” evolution. We then show how a common type of mutation bias, where detrimental mutations are more common than beneficial mutations, can drive the locking-in of structural hierarchies such as eukaryotism or multicellularity, independently from the environment. Finally, we generalize this result to show how any mutation (or sets of mutations) that creates the possibility of new phenotypes can persist for a very long period of time. That is, innovations that make possible a large range of new phenotypes can become frozen in time. By becoming frozen, these novel structures can no longer change, which means a range of phenotypes also become impossible. This opening and closing of phenotypic space is a new mechanism of macro-evolution.Competing Interest StatementThe authors have declared no competing interest.