RT Journal Article SR Electronic T1 Analysis of the study of the cerebellar pinceau by Korn and Axelrad JF bioRxiv FD Cold Spring Harbor Laboratory SP 001123 DO 10.1101/001123 A1 Antonin Blot A1 Boris Barbour YR 2013 UL http://biorxiv.org/content/early/2013/12/03/001123.abstract AB The axon initial segment of each cerebellar Purkinje cell is ensheathed by basket cell axons in a structure called the pinceau, which is largely devoid of chemical synapses and gap junctions. These facts and ultrastructural similarities with the axon cap of the teleost Mauthner cell led to the conjecture that the pinceau mediates ephaptic (via the extracellular field) inhibition. Korn and Axelrad published a study in 1980 in which they reported confirmation of this conjecture. We have analysed their results and show that most are likely to be explained by an artefactual signal arising from the massive stimulation of parallel fibres they employed. We reproduce their experiments and confirm that all of their results are consistent with this artefact. Their data therefore provide no evidence regarding the operation of the pinceau.