TY - JOUR T1 - Exact firing time statistics of neurons driven by discrete inhibitory noise JF - bioRxiv DO - 10.1101/116467 SP - 116467 AU - Simona Olmi AU - David Angulo-Garcia AU - Alberto Imparato AU - Alessandro Torcini Y1 - 2017/01/01 UR - http://biorxiv.org/content/early/2017/03/14/116467.abstract N2 - Neurons in the intact brain receive a continuous and irregular synaptic bombardment from excitatory and inhibitory presynaptic neurons, which determines the firing activity of the stimulated neuron. In orderto investigate the influence of inhibitory stimulation on the firing time statistics, we consider Leaky Integrate-and-Fire neurons subject to inhibitory instantaneous postsynaptic potentials. In particular, we report exact results for the firing rate, the coefficient of variation and the spike train spectrum for various synaptic weight distributions. Our results are not limited to stimulations of infinitesimal amplitude, but they apply as well to finite amplitude post-synaptic potentials, thus being able to capture the effect of rare and large spikes. The developed methods are able to reproduce also the average firing properties of heterogeneous neuronal populations. ER -