PT - JOURNAL ARTICLE AU - Quentin Geissmann AU - Luis Garcia Rodriguez AU - Esteban J Beckwith AU - Alice S French AU - Arian R Jamasb AU - Giorgio F Gilestro TI - Ethoscopes: an open platform for high-throughput <em>ethomics</em> AID - 10.1101/113647 DP - 2017 Jan 01 TA - bioRxiv PG - 113647 4099 - http://biorxiv.org/content/early/2017/03/24/113647.short 4100 - http://biorxiv.org/content/early/2017/03/24/113647.full AB - We present ethoscopes, machines for high-throughput ethomics in Drosophila and other small animals. Ethoscopes provide four unique features: they provide a software and hardware solution that is reproducible, scalable and open-source; they perform not just real-time tracking, but faithful real-time profiling of behaviour using a supervised machine learning algorithm; they can stimulate flies in a feedback-loop mode; they are highly customisable and open source.Authors’ contributions QG, LGR and GFG designed the platform; QG and LGR wrote the software; QG and EJB performed the experiments; ARJ contributed the optomotor module; ASF contributed the AGO module; all authors contributed the manuscript.Competing interests The authors declare that no competing interests exist.