RT Journal Article
SR Electronic
T1 DNA Nanostar Structures with Tunable Auxetic Properties
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2023.12.22.573109
DO 10.1101/2023.12.22.573109
A1 Du, Yancheng
A1 Li, Ruixin
A1 Madhvacharyula, Anirudh S.
A1 Swett, Alexander A.
A1 Choi, Jong Hyun
YR 2023
UL http://biorxiv.org/content/early/2023/12/23/2023.12.22.573109.abstract
AB Auxetic structures are unique with a negative Poisson’s ratio. Unlike regular materials, they response to external loading with simultaneous expansion or compression in all directions, rendering powerful properties advantageous in diverse applications from manufacturing to space engineering. The auxetic behaviors are determined by structural design and architecture. Such structures have been discovered in natural crystals and demonstrated synthetically with bulk materials. Recent development of DNA-based structures has pushed the unit cell size to nanometer scale. DNA nanotechnology utilizes sequence complementarity between nucleotides. By combining sequence designs with programmable self-assembly, it is possible to construct complex structures with nanoscale accuracy and to perform dynamic reconfigurations. Herein, we report a novel design of auxetic nanostars with sliding behaviors using DNA origami. Our proposed structure, inspired by an Islamic pattern, demonstrates a unit cell with two distinct reconfigurations by programming directed sliding mechanisms. Compared to previous metamaterials, the DNA nanostars show an architecture with tunable auxetic properties for the first time. We envision that this strategy may form the basis of novel metastructures with adaptability and open new possibilities in bioengineering.Competing Interest StatementThe authors have declared no competing interest.