TY - JOUR T1 - Comparative genomic evidence for self-domestication in <em>Homo sapiens</em> JF - bioRxiv DO - 10.1101/125799 SP - 125799 AU - Constantina Theofanopoulou AU - Simone Gastaldon AU - Thomas O’Rourke AU - Bridget D. Samuels AU - Angela Messner AU - Pedro Tiago Martins AU - Francesco Delogu AU - Saleh Alamri AU - Boeckx Cedric Y1 - 2017/01/01 UR - http://biorxiv.org/content/early/2017/04/08/125799.abstract N2 - This study identifies and analyzes statistically significant overlaps between selective sweep screens in anatomically modern humans and several domesticated species. The results obtained suggest that (paleo-)genomic data can be exploited to complement the fossil record and support the idea of self-domestication in Homo sapiens, a process that likely intensified as our species populated its niche. Our analysis lends support to attempts to capture the “domestication syndrome” in terms of alterations to certain signaling pathways and cell lineages, such as the neural crest. ER -