RT Journal Article
SR Electronic
T1 Gene annotation bias impedes biomedical research
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 133108
DO 10.1101/133108
A1 Winston A. Haynes
A1 Aurelie Tomczak
A1 Purvesh Khatri
YR 2017
UL http://biorxiv.org/content/early/2017/05/02/133108.abstract
AB We found tremendous inequality across gene and protein annotation resources. We observe that this bias leads biomedical researchers to focus on richly annotated genes instead of those with the strongest molecular data. We advocate for researchers to reduce these biases by pursuing data-driven hypotheses.