RT Journal Article
SR Electronic
T1 Relative phase of distributed oscillatory dynamics implements a working memory in a simple brain
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2024.08.11.607402
DO 10.1101/2024.08.11.607402
A1 Dunn, Raymond L.
A1 Costello, Caitriona
A1 Borchardt, Jackson M.
A1 Sprague, Daniel Y.
A1 Chiu, Grace C.
A1 Miller, Julia M.
A1 L’Etoile, Noelle
A1 Kato, Saul
YR 2024
UL http://biorxiv.org/content/early/2024/08/11/2024.08.11.607402.abstract
AB We report the existence of a working memory system in the nematode C. elegans that is employed for deferred action in a sensory-guided decision-making process. We find that the turn direction of discrete reorientations during navigation is under sensory-guided control and relies on a working memory that can persist over an intervening behavioral sequence. This memory system is implemented by the phasic interaction of two distributed oscillatory dynamical components. The interaction of oscillatory neural ensembles may be a conserved primitive of cognition across the animal kingdom.Competing Interest StatementThe authors have declared no competing interest.