RT Journal Article
SR Electronic
T1 Bibliometric Analysis of Circular RNA Cancer Vaccines and Their Emerging Impact
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2024.08.31.610618
DO 10.1101/2024.08.31.610618
A1 Das, Uddalak
A1 Banerjee, Soupayan
A1 Sarkar, Meghna
YR 2024
UL http://biorxiv.org/content/early/2024/09/03/2024.08.31.610618.abstract
AB Circular RNA (circRNA) vaccines are emerging as a revolutionary strategy in cancer immunotherapy, offering novel mechanisms for inducing robust and durable immune responses. Unlike traditional linear mRNA vaccines, circRNAs exhibit exceptional stability, enhanced translational efficiency, and resistance to exonuclease degradation, making them ideal candidates for vaccine development. Recent studies have shown that circRNA vaccines play an important and specialized role in cancer treatment. However, there are currently no relevant bibliometric studies. This study aimed to apply bibliometrics and scientometrics to summarize the knowledge structure and research hotspots regarding the role of circRNA vaccines in cancer. Publications related to circRNA vaccines in cancer were searched on the Scopus database. VOSviewer and Scopus were used to conduct the analyses. This study summarizes the research trends and development of circRNA vaccines for cancer and also a comparative analysis between mRNA cancer vaccine and circRNA cancer vaccine identifying potential areas of focus, innovation and growth. This information will provide a reference for researchers to studying circRNA vaccines against cancer due to its increasing trends over recent times.Competing Interest StatementThe authors have declared no competing interest.