RT Journal Article
SR Electronic
T1 IntelliProfiler: a novel analytic tool for behavior dynamics of multiple animals in a home cage
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2024.10.23.619967
DO 10.1101/2024.10.23.619967
A1 Ochi, Shohei
A1 Inada, Hitoshi
A1 Osumi, Noriko
YR 2024
UL http://biorxiv.org/content/early/2024/10/26/2024.10.23.619967.abstract
AB There is a growing demand for sophisticated behavioral analysis systems that minimize bias in multi-animal and semi-natural environments. We present “IntelliProfiler,” an advanced system using radio frequency identification (RFID) technology to enable fully automated behavior analyses of multiple mice within a home cage. IntelliProfiler continuously monitors up to 16 mice, capturing both locomotor activity and social dynamics over extended periods. Our findings revealed that male mice maintain broader social distances than females, with group size playing a key role in shaping male social network dynamics. Furthermore, aging in males significantly impacts both locomotor activity and social interaction in a group size-dependent manner. With its ability to provide in-depth analysis of individual and group behaviors, IntelliProfiler offers a novel approach for exploring complex social interactions and group dynamics, advancing the field of behavioral science.Competing Interest StatementThe authors have declared no competing interest.