RT Journal Article
SR Electronic
T1 Vaxrank: A computational tool for designing personalized cancer vaccines
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 142919
DO 10.1101/142919
A1 Rubinsteyn, Alexander
A1 Hodes, Isaac
A1 Kodysh, Julia
A1 Hammerbacher, Jeffrey
YR 2017
UL http://biorxiv.org/content/early/2017/05/27/142919.abstract
AB Therapeutic vaccines targeting mutant tumor antigens (“neoantigens”) are an increasingly popular form of personalized cancer immunotherapy. Vaxrank is a computational tool for selecting neoantigen vaccine peptides from tumor mutations, tumor RNA data, and patient HLA type. Vaxrank is freely available at www.github.com/hammerlab/vaxrank under the Apache 2.0 open source license and can also be installed from the Python Package Index.