RT Journal Article
SR Electronic
T1 FUSTr: a tool to find gene Families Under Selection in Transcriptomes
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 146951
DO 10.1101/146951
A1 T. Jeffrey Cole
A1 Michael S. Brewer
YR 2017
UL http://biorxiv.org/content/early/2017/06/07/146951.abstract
AB FUSTr is a tool for finding genes in transcriptomic datasets under strong positive selection that automatically detects isoform designation patterns in transcriptome assemblies to maximize phylogenetic independence in downstream analysis. When applied to previously studied spider toxin families as well as simulated data, FUSTr successfully grouped coding sequences into proper gene families as well as correctly identified those under strong positive selection. FUSTr provides a tool capable of utilizing multi-processor high-performance computational facilities and is scalable for large transcriptomic biodiversity datasets.Availability FUSTr is freely available under a GNU license and can be downloaded at https://github.com/tijeco/FUSTr.Contact coleti16{at}students.ecu.edu