RT Journal Article
SR Electronic
T1 Multiple antibodies identify Glypican-1 on serum exosomes from patients with pancreatic cancer
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 145706
DO 10.1101/145706
A1 Sonia Melo
A1 Christoph Kahlert
A1 Valerie LeBleu
A1 Raghu Kalluri
YR 2017
UL http://biorxiv.org/content/early/2017/06/08/145706.abstract
AB Glypican-1 was found on the surface of cancer exosomes using multiple antibodies from different sources. These include anti-GPC1 antibodies from ThermoFisher (PA5-28055 and PA-5-24972)1,2, Sigma (SAB270028), Abnova (MAB8351), EMD Millipore (MAB2600)3, SantaCruz4, and R&D Systems (BAF4519)2. Here we report on the specific detection of Glypican-1 on the exosomes derived from the serum of pancreas cancer patients using multiple antibodies.