RT Journal Article SR Electronic T1 A cerebellar mechanism for learning prior distributions of time intervals JF bioRxiv FD Cold Spring Harbor Laboratory SP 155226 DO 10.1101/155226 A1 Devika Narain A1 Mehrdad Jazayeri YR 2017 UL http://biorxiv.org/content/early/2017/06/24/155226.abstract AB Knowledge about the statistical regularities of the world is essential for cognitive and sensorimotor function. In the domain of timing, prior statistics are crucial for optimal prediction, adaptation and planning. Where and how the nervous system encodes temporal statistics, however, is not known. Deriving from physiological and anatomical evidence for cerebellar learning, we develop a computational model that demonstrates how the cerebellum could learn prior distributions of time intervals and support Bayesian temporal estimation. The model shows that salient features observed in human Bayesian time interval estimates can be readily captured by learning in the cerebellar cortex and circuit level computations in the cerebellar deep nuclei.