RT Journal Article
SR Electronic
T1 GIGGLE: a search engine for large-scale integrated genome analysis
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 157735
DO 10.1101/157735
A1 Ryan M. Layer
A1 Brent S. Pedersen
A1 Tonya DiSera
A1 Gabor T. Marth
A1 Jason Gertz
A1 Aaron R. Quinlan
YR 2017
UL http://biorxiv.org/content/early/2017/06/29/157735.abstract
AB GIGGLE is a genomics search engine that identifies and ranks the significance of shared genomic loci between query features and thousands of genome interval files. GIGGLE scales to billions of intervals, is faster (+1,000X) than existing methods, and its speed extends the accessibility and utility of resources such as ENCODE, Roadmap Epigenomics, and GTEX by facilitating data integration and hypothesis generation. GIGGLE is available at https://github.com/ryanlayer/giggle.