RT Journal Article
SR Electronic
T1 Oasis2.0: improved online analysis of small RNA-seq data
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 170738
DO 10.1101/170738
A1 Raza-Ur Rahman
A1 Abhivyakti Gautam
A1 Jörn Bethune
A1 Abdul Sattar
A1 Maksims Fiosins
A1 Daniel Sumner Magruder
A1 Vincenzo Capece
A1 Orr Shomroni
A1 Stefan Bonn
YR 2017
UL http://biorxiv.org/content/early/2017/08/03/170738.abstract
AB Oasis 2 is a new main release of the Oasis web application for the detection, differential expression, and classification of small RNAs in deep sequencing data. Compared to its predecessor Oasis, Oasis 2 features a novel and speed-optimized sRNA detection module that supports the identification of small RNAs in any organism with higher accuracy. Next to the improved detection of small RNAs in a target organism, the software now also recognizes potential cross-species miRNAs and viral and bacterial sRNAs in infected samples. In addition, novel miRNAs can now be queried and visualized interactively, providing essential information for over 700 high-quality miRNA predictions across 14 organisms. Robust biomarker signatures can now be obtained using the novel enhanced classification module. Oasis 2 enables biologists and medical researchers to rapidly analyze and query small RNA deep sequencing data with improved precision, recall, and speed, in an interactive and user-friendly environment.Availability and Implementation: Oasis 2 is implemented in Java, J2EE, mysql, Python, R, PHP and JavaScript. It is freely available at http://oasis.dzne.de