RT Journal Article
SR Electronic
T1 Differential spatiotemporal representations along the hippocampal long axis in humans
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 179655
DO 10.1101/179655
A1 Iva K. Brunec
A1 Buddhika Bellana
A1 Jason D. Ozubko
A1 Vincent Man
A1 Jessica Robin
A1 Zhong-Xu Liu
A1 Cheryl Grady
A1 R. Shayna Rosenbaum
A1 Gordon Winocur
A1 Morgan D. Barense
A1 Morris Moscovitch
YR 2017
UL http://biorxiv.org/content/early/2017/08/24/179655.abstract
AB Increased place field size and signal autocorrelation along the dorsoventral hippocampal axis in rodents are considered a fundamental aspect of hippocampal organization, yet such evidence is lacking in humans. Using fMRI, we report corresponding evidence of increasing neural similarity from posterior to anterior hippocampus (dorsoventral homologues) in humans. These findings help account for observed shifting in representational granularity, from global context (anterior) to local details (posterior), along the hippocampal axis.