PT - JOURNAL ARTICLE AU - Lin Cong AU - Zeguan Wang AU - Yuming Chai AU - Wei Hang AU - Chunfeng Shang AU - Wenbin Yang AU - Lu Bai AU - Jiulin Du AU - Kai Wang AU - Quan Wen TI - Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (<em>Danio rerio</em>) AID - 10.1101/131532 DP - 2017 Jan 01 TA - bioRxiv PG - 131532 4099 - http://biorxiv.org/content/early/2017/08/25/131532.short 4100 - http://biorxiv.org/content/early/2017/08/25/131532.full AB - The internal brain dynamics that link sensation and action are arguably better studied during natural animal behaviors. Here we report on a novel volume imaging and 3D tracking technique that monitors whole brain neural activity in freely swimming larval zebrafish (Danio rerio). We demonstrated the capability of our system through functional imaging of neural activity during visually evoked and prey capture behaviors in larval zebrafish.