RT Journal Article SR Electronic T1 Parallel sequencing lives, or what makes large sequencing projects successful JF bioRxiv FD Cold Spring Harbor Laboratory SP 136358 DO 10.1101/136358 A1 Quilez, Javier A1 Vidal, Enrique A1 Dily, François Le A1 Serra, François A1 Cuartero, Yasmina A1 Stadhouders, Ralph A1 Graf, Thomas A1 Marti-Renom, Marc A. A1 Beato, Miguel A1 Filion, Guillaume YR 2017 UL http://biorxiv.org/content/early/2017/08/29/136358.abstract AB T47D_rep2 and b1913e6c1_51720e9cf were two Hi-C samples. They were born and processed at the same time, yet their fates were very different. The life of b1913e6c1_51720e9cf was simple and fruitful, while that of T47D_rep2 was full of accidents and sorrow. At the heart of these differences lies the fact that b1913e6c1_51720e9cf was born under a lab culture of Documentation, Automation, Traceability, Autonomy and compliance with the FAIR Principles. Their lives are a lesson for those who wish to embark on the journey of managing high throughput sequencing data.