%0 Journal Article %A J. Alexander Bae %A Shang Mu %A Jinseop S. Kim %A Nicholas L. Turner %A Ignacio Tartavull %A Nico Kemnitz %A Chris S. Jordan %A Alex D. Norton %A William M. Silversmith %A Rachel Prentki %A Marissa Sorek %A Celia David %A Devon L. Jones %A Doug Bland %A Amy L. R. Sterling %A Jungman Park %A Kevin L. Briggman %A H. Sebastian Seung %A the EyeWirers %T Structural and functional diversity of a dense sample of retinal ganglion cells %D 2017 %R 10.1101/182758 %J bioRxiv %P 182758 %X To aid understanding of retinal structure and function, we present as an online resource the dendritic arbors and visual responses of ganglion cells in a single patch of mouse retina. We divide the inner plexiform layer, which contains the dendritic arbors of ganglion cells, into four sublaminae defined by a purely anatomical principle of arbor segregation. The sublaminae serve as the starting point for a hierarchical clustering of our ganglion cells. We propose and apply a quantitative criterion for validating a cluster as a ganglion cell type: the aggregate neurite density of a type should be approximately uniform (“density conservation”). Finally, we find that ganglion cells arborizing in the inner marginal sublamina of the inner plexi-form layer exhibit significantly more sustained visual responses on average. %U https://www.biorxiv.org/content/biorxiv/early/2017/08/31/182758.full.pdf