RT Journal Article
SR Electronic
T1 An almost nearly optimal sequential testing approach to permutation-based association testing
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 186361
DO 10.1101/186361
A1 Julian Hecker
A1 Ingo Ruczinski
A1 Brent Coull
A1 Christoph Lange
YR 2017
UL http://biorxiv.org/content/early/2017/09/12/186361.abstract
AB The following technical report describes the technical details for the implementation of a sequential testing approach to permutation-based association testing in whole-genome sequencing studies. The sequential testing approach enables to control the probability of a type 1 and type 2 error at arbitrary small pre-specified levels and approaches the theoretical minimum of expected number of required permutations as these levels go to zero.