PT - JOURNAL ARTICLE AU - Thomas J. Hardcastle AU - Irene Papatheodorou TI - clusterSeq: methods for identifying co-expression in high-throughput sequencing data AID - 10.1101/188581 DP - 2017 Jan 01 TA - bioRxiv PG - 188581 4099 - http://biorxiv.org/content/early/2017/09/13/188581.short 4100 - http://biorxiv.org/content/early/2017/09/13/188581.full AB - Summary: Identifying gene co-expression is a significant step in understanding functional relationships between genes. Existing methods primarily depend on analyses of correlation between pairs of genes; however, this neglects structural elements between experimental conditions. We present a novel approach to identifying clusters of co-expressed genes that incorporates these structures.Availability: The methods are released on Bioconductor as the clusterSeq package (https://bioconductor.org/packages/release/bioc/html/clusterSeq.html).Contact: tjh48@cam.ac.uk