PT  - JOURNAL ARTICLE
AU  - Goudarzi, Morteza Moazami
AU  - Cromer, Jason
AU  - Roy, Jefferson
AU  - Miller, Earl K.
TI  - Neuronal rhythms orchestrate cell assembles to distinguish perceptual categories
AID  - 10.1101/191247
DP  - 2017 Jan 01
TA  - bioRxiv
PG  - 191247
4099  - http://biorxiv.org/content/early/2017/09/20/191247.short
4100  - http://biorxiv.org/content/early/2017/09/20/191247.full
AB  - Categories are reflected in the spiking activity of neurons. However, how neurons form ensembles for categories is unclear. To address this, we simultaneously recorded spiking and local field potential (LFP) activity in the lateral prefrontal cortex (lPFC) of monkeys performing a delayed match to category task with two independent category sets (Animals: Cats vs Dogs; Cars: Sports Cars vs Sedans). We found stimulus and category information in alpha and beta band oscillations. Different category distinctions engaged different frequencies. There was greater spike field coherence (SFC) in alpha (∼8-14 Hz) for Cats and in beta (∼16-22 Hz) for Dogs. Cars showed similar differences, albeit less pronounced: greater alpha SFC for Sedans and greater beta SFC for Sports Cars. Thus, oscillatory rhythms can help coordinate neurons into different ensembles. Engagement of different frequencies may help differentiate the categories.