RT Journal Article
SR Electronic
T1 Theta phase coordinated memory reactivation reoccurs in a slow-oscillatory rhythm during NREM sleep
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 202143
DO 10.1101/202143
A1 Thomas Schreiner
A1 Christian F. Doeller
A1 Ole Jensen
A1 Björn Rasch
A1 Tobias Staudigl
YR 2017
UL http://biorxiv.org/content/early/2017/10/12/202143.abstract
AB It has been proposed that sleep’s contribution to memory consolidation is to reactivate prior encoded information. To elucidate the neural mechanisms carrying reactivation-related mnemonic information, we investigated whether content-specific memory signatures associated with memory reactivation during wakefulness reoccur during subsequent sleep. We show that theta oscillations orchestrate the reactivation of memories, irrespective of the physiological state. Reactivation patterns during sleep autonomously re-emerged at a rate of 1 Hz, indicating a coordination by slow oscillatory activity.