PT  - JOURNAL ARTICLE
AU  - Chung, Moo K.
AU  - Luo, Zhan
AU  - Adluru, Nagesh
AU  - Alexander, Andrew L.
AU  - Richard, Davidson J.
AU  - Goldsmith, H. Hill
TI  - Heritability of hierarchical structural brain network
AID  - 10.1101/209635
DP  - 2017 Jan 01
TA  - bioRxiv
PG  - 209635
4099  - http://biorxiv.org/content/early/2017/10/27/209635.short
4100  - http://biorxiv.org/content/early/2017/10/27/209635.full
AB  - We present a new structural brain network parcellation scheme that can subdivide existing parcellations into smaller subregions in a hierarchically nested fashion. The hierarchical parcellation was used to build multilayer convolutional structural brain networks that preserve topology across different network scales. As an application, we applied the method to diffusion weighted imaging study of 111 twin pairs. The genetic contribution of the whole brain structural connectivity was determined. We showed that the overall heritability is consistent across different network scales.