RT Journal Article
SR Electronic
T1 Heritability of hierarchical structural brain network
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 209635
DO 10.1101/209635
A1 Chung, Moo K.
A1 Luo, Zhan
A1 Adluru, Nagesh
A1 Alexander, Andrew L.
A1 Richard, Davidson J.
A1 Goldsmith, H. Hill
YR 2017
UL http://biorxiv.org/content/early/2017/10/27/209635.abstract
AB We present a new structural brain network parcellation scheme that can subdivide existing parcellations into smaller subregions in a hierarchically nested fashion. The hierarchical parcellation was used to build multilayer convolutional structural brain networks that preserve topology across different network scales. As an application, we applied the method to diffusion weighted imaging study of 111 twin pairs. The genetic contribution of the whole brain structural connectivity was determined. We showed that the overall heritability is consistent across different network scales.