RT Journal Article
SR Electronic
T1 Stomach-brain synchrony binds neural representations of the body in a novel, delayed-connectivity resting-state network
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 217604
DO 10.1101/217604
A1 Ignacio Rebollo
A1 Anne-Dominique Devauchelle
A1 Benoît Béranger
A1 Catherine Tallon-Baudry
YR 2017
UL http://biorxiv.org/content/early/2017/11/10/217604.abstract
AB Resting-state networks offer a unique window into the brain’s functional architecture, but their characterization remains limited to instantaneous connectivity thus far. Here, we describe a novel resting-state network based on the delayed connectivity between the brain and the slow electrical rhythm (0.05 Hz) generated in the stomach. The gastric network cuts across classical resting-state networks with little overlap with autonomic regulation areas. This network is composed of regions with convergent functional properties involved in mapping bodily space through touch, action or vision, as well as mapping external space in bodily coordinates. The network is characterized by a precise temporal sequence of activations within a gastric cycle, beginning with somato-motor cortices and ending with the extrastriate body area and dorsal precuneus. Our results demonstrate that canonical resting-state networks based on instantaneous connectivity represent only one of the possible partitions of the brain into coherent networks based on temporal dynamics.