TY - JOUR T1 - A How-To guide to: Quantitative high-speed video profiling to discriminate between variants of primary ciliary dyskinesia JF - bioRxiv DO - 10.1101/614966 SP - 614966 AU - M. Chioccioli AU - L. Feriani AU - Q. Nguyen AU - J. Kotar AU - S. D. Dell AU - V. Mennella AU - I. Amirav AU - P. Cicuta Y1 - 2019/01/01 UR - http://biorxiv.org/content/early/2019/04/20/614966.abstract N2 - This document presents detailed steps to analysing the waveforms of beating cilia, measured in high speed video microscopy. We show that in the case of PCD caused by mutations in DNAH11 and HYDIN the classification by a handful of parameters describing ciliary dynamics allows to distinguish the genotype, as well as (much more easily) distinguishing healthy from PCD samples. This document is intended to complement the brief highlight (1) and presents the details of the datasets used in that letter. ER -