%0 Journal Article %A Jia-Xing Yue %A Gianni Liti %T simuG: a general-purpose genome simulator %D 2019 %R 10.1101/491498 %J bioRxiv %P 491498 %X Summary Simulated genomes with pre-defined and random genomic variants can be very useful for benchmarking genomic and bioinformatics analyses. Here we introduce simuG, a lightweight tool for simulating the full-spectrum of genomic variants (SNPs, INDELs, CNVs, inversions and translocations) for any organisms (including human). The simplicity and versatility of simuG makes it a unique general purpose genome simulator for a wide-range of simulation-based applications.Availability and implementation Code in Perl along with user manual and testing data is available at https://github.com/yjx1217/simuG. This software is free for use under the MIT license. %U https://www.biorxiv.org/content/biorxiv/early/2019/04/30/491498.full.pdf