PT  - JOURNAL ARTICLE
AU  - Joshua T. Vogelstein
AU  - Eric W. Bridgeford
AU  - Benjamin D. Pedigo
AU  - Jaewon Chung
AU  - Keith Levin
AU  - Brett Mensh
AU  - Carey E. Priebe
TI  - Connectal Coding: Discovering the Structures Linking Cognitive Phenotypes to Individual Histories
AID  - 10.1101/610501
DP  - 2019 Jan 01
TA  - bioRxiv
PG  - 610501
4099  - http://biorxiv.org/content/early/2019/05/02/610501.short
4100  - http://biorxiv.org/content/early/2019/05/02/610501.full
AB  - Cognitive phenotypes characterize our memories, beliefs, skills, and preferences, and arise from our ancestral, developmental, and experiential histories. These histories are written into our brain structure through the building and modification of various brain circuits. Connectal coding, by way of analogy with neural coding, is the art, study, and practice of identifying the network structures that link cognitive phenomena to individual histories. We propose a formal statistical framework for connectal coding and demonstrate its utility in several applications spanning experimental modalities and phylogeny.