RT Journal Article
SR Electronic
T1 Connectal Coding: Discovering the Structures Linking Cognitive Phenotypes to Individual Histories
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 610501
DO 10.1101/610501
A1 Joshua T. Vogelstein
A1 Eric W. Bridgeford
A1 Benjamin D. Pedigo
A1 Jaewon Chung
A1 Keith Levin
A1 Brett Mensh
A1 Carey E. Priebe
YR 2019
UL http://biorxiv.org/content/early/2019/05/02/610501.abstract
AB Cognitive phenotypes characterize our memories, beliefs, skills, and preferences, and arise from our ancestral, developmental, and experiential histories. These histories are written into our brain structure through the building and modification of various brain circuits. Connectal coding, by way of analogy with neural coding, is the art, study, and practice of identifying the network structures that link cognitive phenomena to individual histories. We propose a formal statistical framework for connectal coding and demonstrate its utility in several applications spanning experimental modalities and phylogeny.