PT  - JOURNAL ARTICLE
AU  - Dewan M. Sarwar
AU  - Yuda Munarko
AU  - David P. Nickerson
TI  - Epithelial Modelling Platform: A Tool for Model Discovery and Assembly with the Physiome Model Repository
AID  - 10.1101/631465
DP  - 2019 Jan 01
TA  - bioRxiv
PG  - 631465
4099  - http://biorxiv.org/content/early/2019/05/08/631465.short
4100  - http://biorxiv.org/content/early/2019/05/08/631465.full
AB  - In this paper we present a web-based platform enabling scientists to construct a novel epithelial transport model to investigate their hypotheses, aided by building on existing models discovered in the Physiome Model Repository (PMR). We have comprehensively annotated a cohort of epithelial transport models deposited in the PMR as a seeding collection of building blocks that are freely available for reuse. On the platform, users are able to semantically display models for visualization, graphical editing, and model assembly. In addition, we leverage web services from the European Bioinformatics Institute (EBI) to help rank similar models based on the suggestions provided by the platform. In addition to potential use in biomedical and clinical research, novice modellers could use our platform as a learning tool. The source code and links to a live demonstration of the platform are available at https://github.com/dewancse/ epithelial-modelling-platform.