PT - JOURNAL ARTICLE AU - Philip A Ewels AU - Alexander Peltzer AU - Sven Fillinger AU - Johannes Alneberg AU - Harshil Patel AU - Andreas Wilm AU - Maxime Ulysse Garcia AU - Paolo Di Tommaso AU - Sven Nahnsen TI - <em>nf-core</em>: Community curated bioinformatics pipelines AID - 10.1101/610741 DP - 2019 Jan 01 TA - bioRxiv PG - 610741 4099 - http://biorxiv.org/content/early/2019/05/26/610741.short 4100 - http://biorxiv.org/content/early/2019/05/26/610741.full AB - The standardization, portability, and reproducibility of analysis pipelines is a renowned problem within the bioinformatics community. Most pipelines are designed for execution on-premise, and the associated software dependencies are tightly coupled with the local compute environment. This leads to poor pipeline portability and reproducibility of the ensuing results - both of which are fundamental requirements for the validation of scientific findings. Here, we introduce nf-core: a framework that provides a community-driven, peer-reviewed platform for the development of best practice analysis pipelines written in Nextflow. Key obstacles in pipeline development such as portability, reproducibility, scalability and unified parallelism are inherently addressed by all nf-core pipelines. We are also continually developing a suite of tools that assist in the creation and development of both new and existing pipelines. Our primary goal is to provide a platform for high-quality, reproducible bioinformatics pipelines that can be utilized across various institutions and research facilities.