RT Journal Article
SR Electronic
T1 Population-based neuroimaging reveals traces of childbirth in the maternal brain
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 650952
DO 10.1101/650952
A1 Ann-Marie G. de Lange
A1 Tobias kaufmann
A1 Dennis van der Meer
A1 Luigi Maglanoc
A1 Dag Alnæs
A1 Torgeir Moberget
A1 Gwenaëlle Douaud
A1 Ole A. Andreassen
A1 Lars T. Westlye
YR 2019
UL http://biorxiv.org/content/early/2019/05/27/650952.abstract
AB Pregnancy and childbirth involve maternal brain adaptations that promote attachment to and protection of the newborn. Using brain imaging and machine learning, we provide evidence for a positive relationship between number of childbirths and a ‘younger-looking’ brain in 12,021 women, which could not be explained by common genetic variation. The findings demonstrate that parity can be linked to brain health later in life.