TY - JOUR T1 - FAIRshake: toolkit to evaluate the findability, accessibility, interoperability, and reusability of research digital resources JF - bioRxiv DO - 10.1101/657676 SP - 657676 AU - Daniel J. B. Clarke AU - Lily Wang AU - Alex Jones AU - Megan L. Wojciechowicz AU - Denis Torre AU - Kathleen M. Jagodnik AU - Sherry L. Jenkins AU - Peter McQuilton AU - Zachary Flamholz AU - Moshe C. Silverstein AU - Brian M. Schilder AU - Kimberly Robasky AU - Claris Castillo AU - Ray Idaszak AU - Stanley C. Ahalt AU - Jason Williams AU - Stephan Schurer AU - Daniel J. Cooper AU - Ricardo de Miranda Azevedo AU - Juergen A. Klenk AU - Melissa A. Haendel AU - Jared Nedzel AU - Paul Avillach AU - Mary E. Shimoyama AU - Rayna M. Harris AU - Meredith Gamble AU - Rudy Poten AU - Amanda L. Charbonneau AU - Jennie Larkin AU - C. Titus Brown AU - Vivien R. Bonazzi AU - Michel J. Dumontier AU - Susanna-Assunta Sansone AU - Avi Ma’ayan Y1 - 2019/01/01 UR - http://biorxiv.org/content/early/2019/06/03/657676.abstract N2 - As more datasets, tools, workflows, APIs, and other digital resources are produced by the research community, it is becoming increasingly difficult to harmonize and organize these efforts for maximal synergistic integrated utilization. The Findable, Accessible, Interoperable, and Reusable (FAIR) guiding principles have prompted many stakeholders to consider strategies for tackling this challenge by making these digital resources follow common standards and best practices so that they can become more integrated and organized. Faced with the question of how to make digital resources more FAIR, it has become imperative to measure what it means to be FAIR. The diversity of resources, communities, and stakeholders have different goals and use cases and this makes assessment of FAIRness particularly challenging. To begin resolving this challenge, the FAIRshake toolkit was developed to enable the establishment of community-driven FAIR metrics and rubrics paired with manual, semi- and fully-automated FAIR assessment capabilities. The FAIRshake toolkit contains a database that lists registered digital resources, with their associated metrics, rubrics, and assessments. The FAIRshake toolkit also has a browser extension and a bookmarklet that enables viewing and submitting assessments from any website. The FAIR assessment results are visualized as an insignia that can be viewed on the FAIRshake website, or embedded within hosting websites. Using FAIRshake, a variety of bioinformatics tools, datasets listed on dbGaP, APIs registered in SmartAPI, workflows in Dockstore, and other biomedical digital resources were manually and automatically assessed for FAIRness. In each case, the assessments revealed room for improvement, which prompted enhancements that significantly upgraded FAIRness scores of several digital resources. ER -