PT - JOURNAL ARTICLE AU - Endre Neparáczki AU - Zoltán Maróti AU - Tibor Kalmár AU - Klaudia Kocsy AU - Kitti Maár AU - Péter Bihari AU - István Nagy AU - Erzsébet Fóthi AU - Ildikó Pap AU - Ágnes Kustár AU - György Pálfi AU - István Raskó AU - Albert Zink AU - Tibor Török TI - Mitogenomic data indicate admixture components of Asian Hun and Srubnaya origin in the Hungarian Conquerors AID - 10.1101/250688 DP - 2018 Jan 01 TA - bioRxiv PG - 250688 4099 - http://biorxiv.org/content/early/2018/01/19/250688.short 4100 - http://biorxiv.org/content/early/2018/01/19/250688.full AB - It has been widely accepted that the Finno-Ugric Hungarian language, originated from proto Uralic people, was brought into the Carpathian Basin by the Hungarian Conquerors. From the middle of the 19th century this view prevailed against the deep-rooted Hungarian Hun tradition, maintained in folk memory as well as in Hungarian and foreign written medieval sources, which claimed that Hungarians were kinsfolk of the Huns. In order to shed light on the genetic origin of the Conquerors we sequenced 102 mitogenomes from early Conqueror cemeteries and compared them to sequences of all available databases. We applied novel population genetic algorithms, named Shared Haplogroup Distance and MITOMIX, to reveal past admixture of maternal lineages. Phylogenetic and population genetic analysis indicated that more than one third of the Conqueror maternal lineages were derived from Central-Inner Asia and their most probable ultimate sources were the Asian Huns. The rest of the lineages most likely originated from the Bronze Age Potapovka-Poltavka-Srubnaya cultures of the Pontic-Caspian steppe, which area was part of the later European Hun empire. Our data give support to the Hungarian Hun tradition and provides indirect evidence for the genetic connection between Asian and European Huns. Available data imply that the Conquerors did not have a major contribution to the gene pool of the Carpathian Basin, raising doubts about the Conqueror origin of Hungarian language.