TY - JOUR T1 - A receptor for herbivore-associated molecular patterns mediates plant immunity JF - bioRxiv DO - 10.1101/679803 SP - 679803 AU - Adam D. Steinbrenner AU - Maria Muñoz-Amatriaín AU - Jessica Montserrat Aguilar Venegas AU - Sassoum Lo AU - Da Shi AU - Nicholas Holton AU - Cyril Zipfel AU - Ruben Abagyan AU - Alisa Huffaker AU - Timothy J. Close AU - Eric A. Schmelz Y1 - 2019/01/01 UR - http://biorxiv.org/content/early/2019/06/22/679803.abstract N2 - Plant-herbivore interactions are ubiquitous across nature and drive major agricultural losses. Inducible defense responses triggered through immune recognition aid in host plant protection; however, specific ligand-receptor pairs mediating the initial perception of herbivory remain unknown. Plants in the subtribe Phaseolinae detect herbivore-associated peptides in caterpillar oral secretions and the defined ligands are proteolytic fragments of chloroplastic ATP synthase termed inceptins. Using forward genetic mapping of inceptin-induced responses, we identify a cowpea (Vigna unguiculata) leucine-rich repeat receptor-like protein as an inceptin receptor (INR) sufficient for elicitor-induced responses and enhanced defense against armyworms (Spodoptera exigua). INR defines a receptor by which plants perceive herbivore-associated molecular patterns (HAMPs) and expands the paradigm of surface immune recognition to attack with mandibles.One Sentence Summary A plant cell surface receptor directly perceives peptides associated with caterpillar herbivory. ER -