PT  - JOURNAL ARTICLE
AU  - Yasmine Aguib
AU  - Mona Allouba
AU  - Alaa Afify
AU  - Sarah Halawa
AU  - Mohamed ElKhateb
AU  - Marina Sous
AU  - Aya Galal
AU  - Eslam Abdelrahman
AU  - Nairouz Shehata
AU  - Amr El Sawy
AU  - Mohamed Maghawry
AU  - Shehab Anwer
AU  - Omnia Kamel
AU  - Wessam El-Mozy
AU  - Hadir Khedr
AU  - Ahmed Essam
AU  - Nagwa Thabet
AU  - Pantazis Theotokis
AU  - Rachel Buchan
AU  - Risha Govind
AU  - Nicola Whiffin
AU  - Roddy Walsh
AU  - Heba Aguib
AU  - Ahmed Elguindy
AU  - Stuart A Cook
AU  - Paul J Barton
AU  - James Ware
AU  - Magdi Yacoub
TI  - Genomics of Egyptian Healthy Volunteers: The EHVol Study
AID  - 10.1101/680520
DP  - 2019 Jan 01
TA  - bioRxiv
PG  - 680520
4099  - http://biorxiv.org/content/early/2019/06/23/680520.short
4100  - http://biorxiv.org/content/early/2019/06/23/680520.full
AB  - Comprehensive genomic databases offer unprecedented opportunities towards effective tailored strategies for the prevention and treatment of disease. The integration of genomic and phenotypic data from diverse ethnic populations is also key to advancements in precision medicine and novel diagnostic technologies. Current reference genomic databases, however, are not representative of the global human population, making variant interpretation challenging and uncertain, especially in underrepresented populations such as the North African population. To address this, a study of 391 Egyptian healthy volunteers (EHVols) was initiated as a milestone towards establishing the 1000 Egyptian Genomes project.