%0 Journal Article %A Sigrid Gouma %A Madison Weirick %A Scott E. Hensley %T Potential antigenic mismatch of the H3N2 component of the 2019 Southern Hemisphere influenza vaccine %D 2019 %R 10.1101/681734 %J bioRxiv %P 681734 %X Here, we find that the egg-adapted H3N2 component of the 2019 Southern Hemisphere influenza vaccine elicits an antibody response in ferrets that is highly focused on antigenic site A of hemagglutinin. This is potentially problematic since most H3N2 viruses currently circulating in the Southern Hemisphere possess antigenic site A substitutions. %U https://www.biorxiv.org/content/biorxiv/early/2019/06/24/681734.full.pdf