PT - JOURNAL ARTICLE AU - Ekman, Axel AU - Weinhardt, Venera AU - Chen, Jian-Hua AU - McDermott, Gerry AU - Le Gros, Mark A. AU - Larabell, Carolyn TI - PSF correction in soft x-ray tomography AID - 10.1101/260737 DP - 2018 Jan 01 TA - bioRxiv PG - 260737 4099 - http://biorxiv.org/content/early/2018/02/05/260737.short 4100 - http://biorxiv.org/content/early/2018/02/05/260737.full AB - In this manuscript, we introduce a linear approximation of the forward model of soft x-ray tomography (SXT), such that the reconstruction is solvable by standard iterative schemes. This linear model takes into account the three-dimensional point spread function (PSF) of the optical system, which consequently enhances the reconstruction data. The feasibility of the model is demonstrated on both simulated and experimental data, based on theoretically estimated and experimentally measured PSFs.